The state-of-the-art ‘preclinical research facility’ spreads over 125,000 Sq.ft designed and built in compliance with Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) and Good Laboratory Practice (GLP) guidelines with inputs from international consultants and experts. The facility is registered with CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals) approval vide No. 1117/PO/bc/07/CPCSEA.
The facility spreads over 5 floors and is designed and built for accommodating animal species, which include - rats, mice, guinea pig, rabbits, hamsters, and canines.
The facility houses best of the instruments from reputed vendors for exceptional quality conduct of the studies. Few of which include –
Biochemical Analyser, Hematology Analyser, Urine Analyser, Reverse Osmosis Water System, Elix Water System, Refrigerated Centrifuge, Mix Mate, Autoclaves (2), Refrigerator, Freezer, Tissue Processor, Tissue Embedder, Flattening Table, Water Bath, Semi Motorized, Microtome, Manual Microtome, Slide Stainer, Cold plate, Inverted Microscope, Magnetic Stirrer, pH meter/Temperature Laboratory Bench, Meter, Hot Plate Stirrer, Autoclave, Animal Weighing Balance (3), AHU Ventilation Units - IVCs (4), Laminar Air Flow (6), Freezer, Balances (6)
Autoclaved water is being used.
Water Contaminants checks:
Routine system checks include general observation of the overall system, the chemical and water storage tanks to assure the system is functioning properly.
A quarterly sample is collected to assess the Bio-Burden, free chlorine levels, Pseudomonas sp., and coliform organisms. The water is also evaluated for contaminant analysis yearly once.
Feed is provided Ad libitum, unless it depends upon the study protocol. sample are sent for nutritional analysis and contamination analysis.
Corncob bedding material is used for rodents and G.Pig maintained in solid bottom cages. The bedding material is autoclaved before use.
Bedding# 7072 [CERTIFIED 118- PURELITE SANITIZED CORN COB (301bs)]
Bedding storage facilities:
Bedding material is stored off the floor, and stacked away from walls to allow for air circulation as well as pest control. A professional exterminator monitors pest control. Dedicated bedding material storage room is provided in Vivarium. Samples from one lot of contact bedding material each year to an outside laboratory to monitor for contaminants such as pesticides, bacteria, yeast, and molds. This analysis and the manufacturer’s analysis are reviewed and maintained on file.
|Photoperiod in hours
|Air Changes Per Hour|
|Rat and Mice||325-400||12:12||15-20|
|Rabbit and G. Pig||325-400||12:12||15-20|
Individual animal room temperature is controlled with an ambient temperature of 18-26°C.
Humidity throughout the building is controlled at 30-70% with general building thermo-hygrometer.
The facility is a conventional facility where the movements is carried out from clean to dirty.
All cages are autoclaved before entering into the clean area. The washing process consists of four stages:
Stage 1 - Water wash – This stage consists of flushing water on the cages. All the solid waste attached to the cage gets cleaned.
Stage 2 – Detergent wash – A detergent solution is used and the cages are soaked for 15 minutes after which they are scrubbed with suitable scrubber, if required.
Stage 3 – Flushing - In this stage the cages are again cleaned under running water.
Stage 4 – Rinsing - In this stage the cages are rinsed with water and finally placed on pallets. These wash cages are later autoclaved before use.