News

2019

ISO 9001:2015

• Vivo Bio Tech Ltd. has received ISO 9001:2015 Certification for Quality Management System.

GLP Surveillance & Scope Expansion

• Successfully completed NGCMA - OECD GLP Surveillance and Scope Extension by introduction of Inhalational studies.

2017

Started Breeding & Distribution of SPF Guinea Pigs

• The Specific Pathogen Free Dunkin Hartley Guinea pig breeders were sourced from Elm Hill Labs, USA in November 2016. SPF Guinea Pigs are bred and maintained in barrier facility within premises of Vivo Bio Tech Ltd. The commercial supplies of Guinea pigs has started from August 2017.
• In India, there is non-availability of specific pathogen free Guinea Pigs for experimentation. Vivo Bio Tech has started the breeding of SPF Guinea pigs.
• The guinea pig, also called the cavy, is a species of rodent belonging to the family Cavidae and the genus Cavia. Despite their common name, these animals are not in the pig family, nor are they from Guinea. Guinea pigs are important research animals as they respond in a similar way as humans to many substances.
• Regulatory guidelines for developmental and reproductive toxicology (DART) studies require selection of "relevant" animal models as determined by kinetic, pharmacological, and toxicological data. Traditionally, rats, mice, and rabbits are the preferred animal models for these studies. However, for test articles that are pharmacologically inactive in the traditional animal models, the guinea pig may be a viable option.
• The SPF Dunkin Hartley Guinea pig breeders were sourced from Elm Hill Labs, USA in November 2016.
• A new modular barrier maintained facility of 3000sft. wascommissioned 50 metre away from VBCNSRS animal facility within premises of Vivo Bio Tech Ltd for housing and breeding of SPF Guinea Pigs.
• The commercial supplies of Guinea pigshas started from August 2017.
• Guinea pigs are maintained in SS pans/ Polypropylene cages and fed with certified SDS guinea pig diet fortified with Vitamin- C (1,015 mg/Kg).
• The health monitoring program is followed for guinea pigs by screening for pathogens as enlisted below:

AAALAC International Accreditation

• Vivo Bio Tech Ltd. was visited on 16 October 2016 for accreditation and declared with Full Accreditation by AAALAC International in May 2017.

GLP Recertification

• Vivo Bio Tech Ltd. was successfully recertified by NGCMA– OECD GLP for Preclinical Services. The scope for preclinical services was expanded for physical chemical testing, Toxicity studies, Mutagenicity studies and residue studies.

Drug Testing Licensing (CDSCO)

• Vivo Bio Tech Ltd. was certified for Drugs Specified in Schedule C and C(1) for Animal testing and received Drug testing Laboratory license wide no. 07/SDPT/TS/2017/AL/G from Drug Control Administration

2016

Central Insecticides Board & Registration Committee (CIBRC)

• Vivo Bio Tech Ltd. was audited by CIBRC in September 2016 and certified for agrochemical testing for toxicology studies.

Partnership for SDS Diets (High Quality Lab Animal Diets)

Diet that is being used for Breeding and maintenance of SPF rodent colonies plays a very crucial role in maintaining the quality as well as their growth patterns. In September 2016, Vivo Bio Tech Ltd. has partnered with UK based Dietex International Ltd. (Special Diets Services) and authorized distributor in India.

Special Diets Services (SDS) is the largest supplier of Laboratory Animal diets in Europe and the only dedicated manufacturer in the UK. SDS has an international reputation for the quality of its diets and manufacturing and storage facilities. SDS has been a Certificated Quality Management since 1991. In 2009, obtained BS EN ISO 9001:2008 Status and in 2010 obtained GMP+ accreditation. All the SDS Lab Animal Diets distributed in India are accompanied with a Special Quality Control (SQC) certificate.

SQC diets are suitable for investigations which are regulated by the standards set by Good Laboratory Practice (GLP). Every single batch of SQC diet receives a Certificate of Analysis following rigorous testing by experienced staff in a modern laboratory. This procedure measures over 40 parameters including major nutrients, vitamins, minerals, heavy metal contaminants, mycotoxins, nitrites, fluoride, pesticide residues and the microbiological status". SDS can tailor its packaging range to the customers' requirements and offer the choice of polythene, vacuum, polyline and irradiated packaging, boxes and large capacity tote bags as well as standard heavy gauge, multi-wall, 12.5kg paper bags. Flexible options for irradiation are available - Diets can be irradiated at UK and shipped directly to customer (OR) can be imported by Vivo Bio Tech and irradiated at Hyderabad and shipped to customer (OR) customer can irradiate the diet after receipt at their facility. Further, Special Quality Control (SQC) diets are provided with a 12 Month Shelf Life from the date of manufacturing.

Based on Customers' requirement, Vivo Bio facilitates direct imports from SDS (UK) or supply from the SDS warehouse at Vivo Bio Tech, Hyderabad. Currently, below mentioned variants are being maintained adequate inventory at Vivo Bio Tech's Ware house -

Cyagen Biosciences and Vivo Bio Tech partner to provide easy access to Genomic Technologies to Indian Biomedical R&D.

Santa Clara, USA and Hyderabad, India, Thursday, September 1, 2016 – Cyagen Biosciences a leader in custom animal models and molecular biology tools and Vivo Bio Tech, a preclinical Contract Research Organization and Specific Pathogen Free Laboratory Animal Commercial Breeder, announced that they have entered into an agreement under which Vivo Bio Tech is appointed as the Authorized Distributor of Cyagen Biosciences’ complete product and service portfolio in India.

Through this partnership, the Indian Biomedical Scientists would have an easy access to cost-effective custom-designed and disease-specific genetically engineered rodent models at a short turnaround time to accelerate their research programs.

“We are excited to announce our new partnership with Vivo Bio Tech, a pioneer in the introduction of locally bred Specific Pathogen Free Laboratory Rodents in India. While Cyagen's clientele span the globe in over fifteen countries including India, this new partnership aims to assist Indian researchers in streamlining and advancing their research by increasing the availability of high quality custom designed animal models, custom vectors, and virus packaging service with highly competitive pricing, fast turnaround time, and excellent customer service” said Cyagen Biosciences Chairman of the Board, Mr. Lance Han.

“We are quite excited to partner with Cyagen Biosciences, one of the leading genomics company with innovative technologies like Turboknockout® - the fastest turnaround for ES-cell based gene targeting and with a track record of successfully delivering more than 2,000 transgenic projects and with a clientele in excess of 300 premier universities and companies worldwide. This partnership takes us yet another step forward towards Vivo Bio Tech’s mission to provide Indian Biomedical Scientists easy access to world class research tools and innovative technologies” said Vivo Bio Tech President Dr. A. Sankaranarayanan.

Vivo Bio Tech will distribute Cyagen’s Animal Models - TurboKnockout® Gene Targeting Mice, Transgenic Rodents, Genome Editing Knockout and Knockin Rodents, PiggyBac Transgenic Mice, Transgenic Mouse Embryos, and Cell & Media products, and Vector building & Packaging Services in India. Vivo Bio Tech shall also offer Custom Breeding and Contract Research Services using Cyagen’s Rodent Models.

About Cyagen Biosciences, Inc. Cyagen Biosciences is a CRO and cell culture product manufacturer headquartered in Silicon Valley, California, and with offices in Germany and China. The company is the world's largest provider of custom-designed transgenic and knockout mouse services with shortest turn-around time, a leader in molecular biology tools and manufacturer of research-use stem cells and related culture reagents. The company’s proprietary new technology, Turboknockout® - an ES cell mediated service provides customers with conditional knockout, reporter knockin and humanization mouse models in as little as 6-8 months.

About Vivo Bio Tech Ltd. Vivo Bio Tech is a Hyderabad based public listed CRO offering services to biomedical industry worldwide in the areas of in-vitro / in-vivo toxicology, pharmacological investigations, analytical and physico-chemical testing. The company is also the largest supplier of locally bred Specific Pathogen Free laboratory rodents in India. The company’s state-of-art 125,000 Sq.ft. preclinical research facility is NGCMA OECD-GLP certified and AAALACi accredited.

For Media Inquiries
Cyagen Biosciences, Inc.
Dr. Austin Jelcick
Director of Marketing
P. +1-800-921-8930
E. service@cyagen.us

Vivo Bio Tech Ltd.
Mr. Kalyan Korisapati
COO & Head – BD
P. +91-8454-244-555
E. kalyan@vivobio.com

2013

“Vivo Bio to provide international quality lab animals in partnership with Taconic”

Provides Local Researchers with Access to Valuable Animal Models

Hudson, New York and Hyderabad, India, February 6, 2013 – Taconic, a leading provider of life sciences solutions, and Vivo Bio Tech Ltd., a full-service contract research organization, announced they have entered into an agreement under which Vivo Bio Tech will gain rights to breed and distribute select Taconic mouse and rat models in India. Through this arrangement, the two companies will greatly improve the availability of high-quality animals for biomedical researchin India.

The pharmaceutical and biotechnology industry in India is growing at an estimated rate of 12 percent and 20 percent annually – through a combination of new in-house drug development projects and collaboration with western companies – making it a hub for biomedical innovation. The Indian CRO industry is estimated to grow at a CAGR of 31 percent to reach USD 3 billion by the year 2015.

“One of the greatest obstacles to drug discovery in the region is the lack of a local supply of quality laboratory animals,” noted Todd Little, Taconic President and CEO. “Together, Taconic and Vivo Bio Tech will address that challenge by significantly improving investigators’ access to animal models that are proven to be highly valuable to biomedical research, yet unavailable in the local market.”

“With access to high-quality lab animal models from a world leader in the field, Vivo Bio Tech is poised to become the preferred provider of research animal models and contract research services in the rapidly growing pharmaceutical and biotechnology markets in India,” said Vivo Bio Tech Chief Executive Officer Dr. A. Sankaranarayanan.

Vivo Bio Tech will breed and distribute select Taconic animal models, including a variety of inbred and outbred mice and rats, as well as the proprietary Taconic Knockout Repository of more than 4,000 knockout lines, .

“The Taconic Knockout Repository eliminates the time traditionally required for model design and development, which can speed drug development for investigators in the region,” Mr. Little said. The agreement gives the Indian pharmaceutical &biotech research community access to Taconic’s advanced scientific services, including model derivation, cryopreservation, genotyping, health assessment, and custom model generation.

All local breeding will be done at Vivo Bio Tech’s 125,000-square-foot pre-clinical research facility in Andhra Pradesh, India. The facility is accredited by AAALAC (Association for Assessment and Accreditation of Laboratory Animal Care) and registered with CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals) for breeding and commercialization of Murine Pathogen Free™ (MPF™) animals. Throughout the breeding process, Vivo Bio Tech’s highly qualified and well-trained staff will follow Taconic’s rigorous standard operating procedures to ensure quality and integrity.

About Vivo Bio Tech Ltd.
Vivo Bio Tech (based in Andhra Pradesh, India) is a full service CRO offering drug development and discovery services to pharmaceutical and biotech companies worldwide in accordance with OECD-GLP, and AAALAC guidelines. The company offers services in the areas of in-vitro, in-vivo, toxicity studies, pharmacological investigations, pharmacokinetic and toxicokinetic studies.

About Taconic
Taconic is an industry leader providing life science solutions to researchers worldwide for more than 60 years. Taconic accelerates drug discovery by providing fast, convenient access to a full suite of more than 4,000 off-the-shelf in vivo mouse and rat models, as well as custom designed models. Taconic provides study-ready cohorts, including tissue or genetically humanized models, supported by reliable data that can advance early development work. Our scientific expertise, innovative technology and breeding services, enables researchers to confidently partner with Taconic for their entire spectrum of in vivo resource needs. Additional information about Taconic is available at www.taconic.com.

For Taconic media inquiries:
Susan Fogt
Marketing Communications
518.697.3962
susan.fogt@taconic.com

For Vivo Bio Tech Ltd inquiries:
Kalyan Kumar Korisapati
Business Development
+91-40-27890662
kalyan@vivobio.com

2011

• Vivo Bio Tech preclinical research facility received ‘Full Accreditation’ by AAALAC International.

2010

• Commenced operations of 125,000 Sq.ft preclinical research facility – Small Animals (Rats, Mice, Rabbits, Hamsters and Guinea Pigs)

2009

• Appointed Dr. A Sankaranarayanan, Ph.D., F.C.P. as Chief Executive Officer and Whole Time Director of the company
• Received SEZ gazette notification from Government of India, for the company’s land (10.93 hectares) at Pregnapur for developing biotech specific Special Economic Zone vide No. F.1/139/2007

2008

2007