SPF Mice - Inbred

BALB/c

Nomenclature: BALB/cAnNTac

Model Description:

• A general purpose inbred strain for many different research disciplines
• Often used for the production of monoclonal antibodies using hybridomas of BALB/c spleen cell origin
• It exhibits good breeding performance and long reproductive life span

Origin: The BALB/c inbred model was first bred by Bagg et al. MacDowell received stock from Bagg in 1923 which were then inbred. Snell received stock from MacDowell in 1932. Andervont received stock from Snell in 1935. NIH received stock at F72 from Andervont in 1951. Taconic's BALB/c mice originated from NIH at F184 prior to 1988. Taconic received litters at F184 from the NIH Animal Genetic Resource in 1997. The mice were derived by embryo transfer in 1998. The Taconic foundation colony was at F229 in 2005. Vivo Bio Tech received the breeders in April 2011 from Taconic.

Color: Albino

Coat Color Loci: Tyrp1b, Tyrc

Health Standard: MPF^TM (Murine Pathogen Free^TM)

C57BL/6

Nomenclature: C57BL/6NTac

Model Description:

• The most widely used inbred as the genetic background for transgenic and mutant mice
• Popular in research applications of oncology, immunology and toxicology

Origin: C57BL/6 litters were received in 1991 at F151 from the NIH Animal Genetic Resource. Cesarean derived in 1991 at Taconic, a foundation colony is maintained in gnotobiotic isolators. Origin is as follows: to NIH in 1951 from Jax at F32; to Jax in 1948 from Hall. Vivo Bio Tech received the breeders in June 2013 from Taconic.

Color: Black

Coat Color Loci: a

Health Standard: MPF^TM (Murine Pathogen Free^TM)